No matter if its hosted on Azure GCP or AWS, latency is real. Cloud providers doesn't magically eliminates the Geography and phhysics. Private network don't eliminates latency magically. In general, Any small latency hike can potentially create performance bottlenecks for write operations in strong consistency DB like postgres or MySQL because each write operation go through a round trip from your server to remote planetscale server that create transaction overhead. Complex transactions with multiple statements can amplify this latency due to this round trip. But you could potentially reduce this latency by hosting your app near to where planet scale host their DB cluster though. But that is a dependency or compromise. Edit: A few writes per second? Probably fine. Hundreds of writes per second? Those extra milliseconds become a real bottleneck.