I think it will mostly impact cap-exempt employers. For example, universities typically use H-1B for new faculty hires, as the visa is available quickly and without too much effort. But if the visa costs $100k, the university will probably skip international applicants, because the hiring department rarely has that much money it is allowed to use freely.

Research universities could probably use O-1, as the requirements for O-1A are lower than the bar for getting a tenure-track position. So they would effectively pay $10k to a lawyer rather than $100k to the government.