Small caliber, lots of plastic, short lifespan, unreliable.
Most serious 3D printed guns have at least a metal barrel. Often, 3D printed guns are just a lower receiver, that is the part you hold in your hand, the parts that actually fire the bullets (barrel, pin, slide, etc...) are bought off the shelf from real gun manufacturers.
This is a workaround for some laws that considers gun parts to not be a gun. For example, outside of a gun, a barrel is just a metal pipe and can be traded freely. The part that makes a gun a gun is the lower receiver, and you can 3D print that in plastic and still get good performance. In fact, Glock makes this part in plastic and these are some of the most popular and proven guns in the world.