Not sure why digital artists get mad when I ask. They’re no Michelangelo.
This isn't me saying digital artists need to practice mixing physical pigment, but anecdotally, every single professional digital artist I know has studied physical paint -- some started there, while others ended up there despite starting out and being really good digitally. But once the latter group hit a plateau, they felt something was lacking, and going back to the fundamentals lifted them even higher.
I can tell you with confidence that physical color mixing itself is a really small part of what makes a good traditional artist, and I am indeed talking about realistic paintings. All the art fundamentals are exactly the same, wether you do digital art or traditional oil, there are just some technical differences on top. I have been learning digital painting for a few years and the hardest things to learn about color were identical to traditional painters. In fact, after years of learning digital painting and about colors, it only took me a couple of days to understand and perform traditional color mixing with oil. The difficult part is knowing what colors you need, not how to get there (mixing, using the sliders, etc.)
And just to add a small bit here: digital artist also color mix all the time and need to know how it works, the difference here is that mixing is additive instead of subtractive.
Do you sneer at those who use industrial pigments instead catching and crushing their own cochineal beetles?
And to add, like many of his contemporaries, Michelangelo likely didn’t do much of the painting that’s attributed to him.