This means that frame numbers in a FLAC file can go up to 2^36-1, so a FLAC file can have up to 68,719,476,735 frames. If it was recorded at a 48kHz sample rate, there will be 48,000 frames per second, meaning a FLAC file at 48kHz sample rate can (in theory) be 14.3 million seconds long, or 165.7 days long.
So if Unicode ever needs to encode 68.7 billion characters, well, extended seven-byte UTF-8 will be ready and waiting. :-D