I am a synthetic biologist, and I use AI a lot for my work. And it constantly denies my questions RIGHT NOW. But of course OpenAI and Anthropic have to implement more - from the GPT5 introduction: "robust safety stack with a multilayered defense system for biology"

While that sounds nice and all, in practical terms, they already ban many of my questions. This just means they're going to lobotomize the model more and more for my field because of the so-called "experts". I am an expert. I can easily go read the papers myself. I could create a biological weapon if I wanted to with pretty much zero papers at all, since I have backups of genbank and the like (just like most chemical engineers could create explosives if they wanted to). But they are specifically targeting my field, because they're from OpenAI and they know what is best.

It just sucks that some of the best tools for learning are being lobotomized specifically for my field because of people in AI believe that knowledge should be kept secret. It's extremely antithetical to the hacker spirit that knowledge should be free.

That said, deep research and those features make it very difficult to switch, but I definitely have to try harder now that I see where the wind is blowing.