the analogy to 14th century Americas would be that aliens arrive, have technology for resource extraction, this disrupts the economics of the existing civilization, which then orients itself to this new technological power and factions compete to dominate brokerage of it among themselves, or to destroy it. the aliens need to secure their resource supply lines from the native factions, and when there is no peace to be had, they fight the way they know how, which wipes most of them out, or they leave and come back in a more evolved millenium.
the cultures that were strong enough to adapt, survived. the ones that weren't able to adapt, died. in a sense it was a case of the meek inheriting the earth, where natives who fought against alien technology lost, and the people in ones that adapted, lived to survive to today.
but the comparison breaks down when you substitute boats for craft capable of relativistic speeds. the sophistication required to do faster than light travel is too high to make unforced errors like that, imo.
