So you don't actually want the power to be at 12V for very long in a power dense rack. Their spec sheet says that each rack can pull 15KW. And that's wired for 208 or 3-phase power. That's 10 hair dryers of power per rack, so yeah maybe you shouldn't step it down until the last responsible moment.
Do any parts of the rack run at the full 54V? That would make for some very nice cooling fans.
We do run the 54V to our fans (in both sleds and switches) without additional DC-DC conversion as those can be fairly power hungry and we can buy reliable fans that are rated for this voltage.
Our sleds actually don't connect directly to the bus bar to help mitigate some of the "oops" factor as they're going to be potentially mated and unmated buy customers as they reconfigure, upgrade or support things. The sled cubbies are wired to the bus-bar and support hot insertion of the sleds. And yes, while possible, an in-field replacement of the bus bar wouldn't be fun, but in our design it's a big copper bar hidden away so the risk of damage or dropping stuff into is minimal.
So our 12V IBC design gets us into more normal range for commodity point-of-load supplies, and balances the losses due to higher current at 12V vs the complexity of dealing with 54V all over the boards. For the AMD parts, we also have to have supplies that deal with SVI2 or SVI3 where the part itself can adjust its voltage at run-time for efficiency. These are pretty complicated devices (like the RAA228218) that we're happy to not have to design ourselves and they have expected operating envelopes for their supply-side rails that don't work at 54V.
As with all things engineering is a series of tradeoffs and right now, an IBC from 54V to 12V has been a reasonable design point for us.