There are techniques that work on modifying nuclear DNA but from my understanding it's much harder (like using CRISPR) and has a lot more risks for things like causing cancer due to off-site editing.
The scales that this technology works is mind-boggling. 10^12 to 10^14 per kg of body weight of individual viral particles that all must do the same thing, and work correctly at scale. Even a few errors could cause serious problems.