Yes I have, I worked with it for years, there's the officially supported standards and then there's the buggy reality you have to deal with. I've encountered bugs with backgrounds, zIndex, videos, forms, localStorage, SVGs, all basic browser features.
Then Safari also is the last non-evergreen browser so it's the slowest to update compared to all the other browsers. If you have a bug, there's a good chance you'll have it for years