What Iran does next depends on the extent of the damage. It could be nothing. It could be a token response. It could be escalation.
But so far Iran has been the only rational actor in this region. Iran has been attacked with justification. Anytime someone says "preemptive strike" they mean "attack without justification". Their responses have been measured, rational, justified and proportionate.
When Israel tried to previously escalate the conflict with Iran and drag the US into war with Iran, Iran just didn't take the bait. And this is despite Israel assassinating government officials, bombing Iranian embassies and bombing Iran for absolutely no reason.