In my experience it is pretty difficult to make WASM faster than JS unless your JS is really crappy and inefficient to begin with. LLVM-generated WASM is your best bet to surpass vanilla JS, but even then it's not a guarantee, especially when you add js interop overhead in. It sort of depends on the specific thing you are doing.

I've found that as of 2025, Go's WASM generator isn't as good as LLVM and it has been very difficult for me to even get parity with vanilla JS performance. There is supposedly a way to use a subset of go with llvm for faster wasm, but I haven't tried it (https://tinygo.org/).

I'm hoping that Microsoft might eventually use some of their wasm chops to improve GO's native wasm compiler. Their .NET wasm compiler is pretty darn good, especially if you enable AOT.

Interop with a WASM-compiled Go binary from JS will be slower but the WASM binary itself might be a lot faster than a JS implementation, if that makes sense. So it depends on how chatty your interop is. The main place you get bogged down is typically exchanging strings across the boundary between WASM and JS. Exchanging buffers (file data, etc) can also be a source of slowdown.

Very likely. Migrating compute-intensive tasks from JavaScript was one of the explicit goals behind the invention of WASM.