Non-twitch based roguelites make it somewhat easier to learn and deploy those alternate strategies in my experience because you can read a bit of a clue online, think about it, and then play through a round slowly and thoughtfully. In an action game, you know, you pick up the sickle weapon for the first time and you may have literally seconds of experience with it before you die.

I spent some substantial time in Enter the Gungeon but have to admit I kind of bounced off of it for this reason... I don't have the raw time to compensate for the fact that the guns require certain muscle memory for each of them, and the bosses need certain muscle memory for each of them, and the combinations require certain muscle memory... I enjoyed my time and you might say I got close enough to see the light at the end of the tunnel, but I just don't have the time to get there in a game where fractions of a second count.