Python has fully-hashed requirements[1], which is what you'd use to assert the integrity of your dependencies. These work with both `pip` and `uv`. You can't use them to directly import the package, but that's more because "packages" aren't really part of Python's import machinery at all.

(Note that hashes themselves don't make "random scripts" not a security risk, since asserting the hash of malware doesn't make it not-malware. You still need to establish a trust relationship with the hash itself, which decomposes to the basic problem of trust and identity distribution.)

[1]: https://pip.pypa.io/en/stable/topics/secure-installs/