Once you do spend a significant amount of money, you'll find that the limits you can set yourself might not even work.
We have a multi-organization OpenAI account and I had set a $4k/month limit on one of the child orgs that was being used for a R&D project. Got billed ~$20k for the project one month and complained that it clearly allowed us to exceed our soft and hard limits. We were told that the limits (which you can set and act like they are a real thing) don't do anything if you have a child organization set up. They refunded us after some persuading and I know it's just normal growing pains for an organization that is undergoing rapid growth and maturity, but was still a little surprising that even the "hard limit" didn't do anything for us!
(Note that this was last year, so this bug is probably long fixed as they have redesigned their portal multiple times now)