htmx-powered applications can be local-only via service workers[1]
i think there is a sense in which htmx vs. react is apples to apples, in that in the common case they are used to build web applications that talk in some manner to a back-end system. On the other hand, it is true that react does require additional support code in order to do that communication.
Regardless of that latter fact, and the fact that htmx does not require a server, there is a large overlap in practical applications that might be built with either, so it is good to know the strengths and weaknesses of both for comparison.
[1] - https://developer.mozilla.org/en-US/docs/Web/API/Service_Wor...