Regardless I’ve heard stories of people having severe long term psychological issues from even relatively light doses, simply because of how their body in particular interacted with the drug.
That is incredibly rare, so rare I can’t find any other documented cases
Edit: did you test it to make sure it was real LSD?
What sort of physician diagnosed you with Serotonin Syndrome? What symptoms did you describe to them, and what criteria/evidence did they use to arrive there? Were they able to use differential diagnosis to rule out other conditions?
Did you return to the same physician after the symptoms ceased?
In fact, Wikipedia's fatal flaw is that we're forced to take medical claims at face-value when they're made by the subject himself.
Personally, my HCPs are very conservative and reluctant to diagnose -- particularly something they can't treat, and especially adverse, untreatable side effects such as "gynecomastia" or "tardive dyskinesia", etc. (Those could contribute to material grounds for lawsuits!) What physician in their right mind would formally diagnose "Serotonin Syndrome", other than one who's on the payroll of a tort/malpractice attorney?
It's interesting for me to balance a distinct tendency for Somatic Symptom Disorder (also shall never be formally diagnosed) with an impulse for self-knowledge, but an aversion to shitty "treatments" that invariably do more harm than good.
Anecdotally, ayuasca quite literally saved my life and helped me tremendously when I was spiraling into a deep depression. Psychedelics when taken responsibly in a controlled environment under supervision can help a lot of people.
To me, it’s interesting to consider the inflammatory aspects – the immunomodulatory effects of LSD and other psychedelics on one hand and alcohol on the other.
It’s well established but little-known that psychedelics have a very significant inflammation-reducing effect which includes drastic reduction of neuroinflammation. (I’m fairly sure that this is a primary reason why they work for depression and anxiety; There’s basically always elevated inflammatory biomarkers with these disorders. Stress is directly causative of neuroimflammation.)
Here’s a really solid review paper from 2017 – today a lot more knowledge has been accumulated: https://www.frontiersin.org/journals/immunology/articles/10....
Alcohol is known to be pro-inflammatory.
I have a hunch that these two disjoint forces on the same physiological systems can have made things worse.
