Sure, but I think the typical path for those who survive and strive in a CS program is to have touched a computer for the first time well before starting work on a college degree for it.

That's like trying to learn a foreign language by picking reading War and Peace in that language, without ever having seen a single translation to that language, or having already read War and Peace in your own. There are a lot of steps you need to take before then.

I would also be pretty surprised if a biology undergrad had never touched a microscope, possibly with the exception of the most impoverished among us. I imagine most people have tried one at some point along the K-12 journey, and there are more introductory treatments of e.g. life science on the way as well.

Starting CS without having "seen or touched" a computer would be like a biology undergrad who wouldn't be able to tell you whether a dog or a tree is a plant or animal.

The difference is that these days the people are surrounded by computers and probably interact with a computer many hours every day, yet they are barely more tech savvy than that first lot who had never seen a computer before.

But so it goes when society moves forward.

If you're saying that at one point in history, a given cohort of new CS students had never seen or touched a computer, I have my doubts, but it depends on how you define CS program. Before computer science was a formalized education stream, it had a variety of other names like "Business Computing" or something related to information technology, but you'd have to go pretty far back imo before you find a whole classroom of entrants into such a program that had never seen or touched a computer. By the time it was called CS, I do find it a bit of a reach that you'd find less than say 10% of students opting into taking it without that low bar being passed.

Likewise the biology example seems strange; sure maybe people haven't used a microscope specifically (unlikely imo), but they very likely have used any number of other implements and taken at least one secondary school biology course

>We do not reject new biology majors because they had never touched a microscope before entering the program.

No but you'd presumably make them take some remedial classes that the mainstream students wouldn't be required to take. Or maybe not, I'm not sure how it works in biology, but in the harder STEM majors, you're generally expected to have some basic knowledge beyond what the 'easy' track at high school required for graduation.