From absolute tropical jungle, through all other climates to frozen high altitude icy desert and all the way back, top point is 5,400m high. Also at one point hinduism of lowlands switches to buddhism. Wild marihuana growing everywhere. Muktinath just after(before) the highest pass is an important sacred and pilgrimage place for 3 different religions.
There is one point in Kali Gandaki gorge where you look left and there is absolute tibetan-style desert with 0 plants, just rocks and dirt, going up to Manang region. You look right and its typical tropical jungle. And in between, in span of maybe 7-8km the whole gradient happens continuously on Annapurna western slopes. Another nice spot is IIRC Marpha where you are looking at almost 5000m pretty much vertical drop on cca top of Dhaulaghiri, its sister 8000m+ peak. Even after 2 weeks of constant exposition to himalayan giants I just stood there in awe.
A life changing experience for me due to various factors and also people met. It has a special place in my heart.