Depends a bit on the "manufactoring". It's not "black"-"white". While it's certainly true for e.g. a brewery or a bike-factory-line, it's less so for aluminum, or chemicals. And even less so for systems like a freezer.
A friend who makes juices and dried fruits on medium scale, plans his production ahead based on the spot pricing: steaming or deep-freezing can be postponed for days, apparently; I helped him with some dashboards and integrations of the pricing-APIs for this.
What I'm trying to say is: yes, a lot of industry won't be able to profit much from these markets. But many can, if they are just willing to change their current ways a little. Not all: many.
