Using Clojure was a bliss. And I'm the person, who didn't want to deal with Lisp at all before (however I always loved FP).
Using pure ClojureScript was for the first a bit limiting because there is no simple way to browse the DOM, e.g. However, with the jayq lib (a jQuery wrapper) it got really simple. You also have to adapt to the fact, that objects like String and Integer (obviously) have another API on the JS platform. Everything else was as beautiful as Clojure — no need for Underscore.js anymore!
I would definitely recommend to anyone to try this stack out. The only concerns I have is the ClojureScript's performance. Due to functional programming approach and laziness it might happen, that a lot more implicit objects will be created, that any GC-strategy of the JS engine might assume. So I have really no idea how the performance of ClojureScript will be in really heavy computational client applications.
