Also any machine learning use cases! There’s a big caveat with uv where they merge your Pipfile and pip installations. For example if you do uv add flask (this is added to pipfile) but then you need to add PyTorch with custom indexes (because most ML libraries distribute driver specific versions) and you do uv pip install PyTorch —-index-url what you end up with is a pipfile.lock that merges the two. uv won’t automatically add your dependency to the Pipfile.

https://pytorch.org/get-started/locally/

You are correct - I should've been more specific. Binding a package(s) to a third party index is currently unsupported (see issue: https://github.com/astral-sh/uv/issues/171) as it is something that pip itself does not support. PDM/Poetry implemented this on their own - though this it's an important feature and as far as I can tell it's coming.