We never generated go code from it, but it took a bit of fine tuning to get generated code that felt at least somewhat ergonomic for Ruby and Typescript. It usually involved using some language specific alternative to protoc for that language because the code generated by protoc itself was practically unreadable. IIRC in the case of Typescript I had to write a script that messed around with the directory structure so you could use sensible import paths and aliases, because TS itself wasn't discovering them automatically without it.
That's stuff you can work with and solve technically. Initial faff but it's one and done. The worst problem I had with it was protobuf3 stating every field is optional by default, and the company I worked at basically developed a custom schema registry setup that declared every field as required by default, with a custom type to mark a field as optional. It turned literally every modification to a protobuf definition into a breaking change and, what's worse, it wasn't done end to end and the failures were silent, so you'd end up with missing data everywhere without knowing it for weeks.