Github is more than a remote host for git repositories. It's become one of the major CDNs for software distributions. Github Pages host a majority of static sites that developer use. You won't be able to use Cargo, Nix, Scoop and other package managers right now because their registries have a critical dependency hosted on Github.
This is not to mention all the projects that rely on Github for project management, devops, community and support desk.
GitHub is also very international, I doubt isolated netziens like those from China are shielded from this outage. I imagine very, very few software shops are unscathed by this. The whole affair is very on brand for 21st century software which is to say pitiful.