A huge class of such systems that are waiting to be created are crowd labor systems. How do you create leaderless organizations that produce what google or boeing or walmart produces and that compensates individuals for performance.
The answer today is a messy unorganized market system. Proper information systems that better organize that would create a lot of value. The analogy would be this site. Thousands of people communicating, without the organizing software it would be much worse (thousands of people standing around talking to each other, the good ideas spoken would not easily reach the top as it does in this organized software system).
tldr; the biggest value opportunities lie in CRUD apps, not the low level code