Sorry, "FFI" was a shorthand for "mixing and matching two languages' GC expectations, memory layouts, ..." and all the overhead associated with merging something opinionated, like Rust, with something dynamic, like Python. You almost certainly _can_ reduce that overhead further, but unless somebody has gone out of their way to do so, the default expectation for cross-language calls like that should be that somebody opted for maintainable code that has actually shipped instead of shaving off every last theoretical bit of overhead.
It's been a few years, so I really can't tell you exactly what the problem was (other than the general observation that you should try to do nontrivial amounts of work in your python extensions rather than trivial amounts), but PyO3 agrees with the general sentiment [0] [1], or at least did at roughly the same time I was working there.
[0] https://github.com/PyO3/pyo3/issues/679
[1] https://github.com/PyO3/pyo3/issues/1470