Businesses are activities undertaken by people but they are also legal entities which have no need to abide by ethical or moral standards, shielding the underlying people from liabilities incurred by such entity. People can't do that.
Citizens need to abide to cultural norms, societal expectations, etc.
Of course everything resolves back to people, in a reductive sense, but those entities (citizens, and businesses) don't have the same standards: morally, ethically, nor legally. Neither do they share the same needs, businesses can by eventuality support the needs of citizens to sell stuff but their only motive is profit-motive, not what's best for citizens.
Business-first is a prerogative of how the USA approaches regulations, it's left first to businesses to regulate themselves until issues mount up to the point where regulations are needed, at that point the businesses have had time to amass power and fight against those. Even in the cases where regulation would be beneficial to society, even in cases where the current regulations which are business-friendly are damaging to society (US's healthcare is a clear example).
It's only meaningless if you don't want to see what it means, citizens needs are considered below the needs of businesses as entities, it's a cultural trait of the USA to let businesses roam more-or-less freely (again, with the exception of some industries) until they cause enough damage to generate popular calls for them to be restrained, at that point is not clear if the government will be able to reign in them. Businesses in the USA have much more power than the people, they make policies, they donate enormous amounts to political campaigns, etc. Citizens can't play in the same field.
There are many cases from the past decades: the global financial meltdown of 2008, the dysfunctional healthcare system, the opioid crisis fueled by a single pharma company, the nosedive of Boeing, etc.
You can attack my point in many ways but not by saying "it's meaningless", businesses interests are, in many cases, not citizens' interests. A very clear example: if a business could they would not hire any Americans, simply because the workforce is expensive, shipping this labour outside of American borders would be great for any business' bottomline, it would not help at all society as a whole. They would do that even if it meant killing their own businesses, since there wouldn't be consumers to buy their products, it wouldn't matter until the issue was extreme enough to require them to actually create a consumer market by employing people in the country.
