Brigaded reports? 4chan solved it by adding a mandatory enum to reports to specify what the report is reporting for. Identifying bad reports and banning users as a result becomes trivial.
Flooding with stories about a particular topic? That's what stickies are for and they work particularly well so that mods can auto-delete any non-sticky stories pertaining to the MOT.
Flamewar on a MOT? Add a sticky to the top of the thread like reddit does saying moderation will be minimal and to enter the thread at your own risk.