IIUC, it depends how the patient would lose that weight. Afaict, these drugs work by lowering appetite overall and making people poop out lots of food before it's fully digested. If the patient macros are still bad, the same proportions as before the drug, they'll have deficiencies such as protein, fiber, electrolytes, vitamins (esp fat-soluble ones), etc. But hopefully it's just for short term. (star)

So to get back to your question, one could lose the weight in the best possible way by correcting their diet, eating less, doing HIIT, fasting, good supplements like creatine, stress reduction through breath work and meditation, and resistance training and end up in a very strong position.

Please anyone correct me on this.

(star) Anecdote about my friend: He went on Metformin for a few years, had lots of diarrhea, and lost about 30 pounds and is skinnier than me. At this point, he could really really get into a strong health position having had that shortcut. His eating habits even got a little better from wearing a glucose monitor. He's sick of the diarrhea which really keeps him from wanting to be out of the house for long, and is slowly looking for some intriguing physical activities. So I think these drugs can help people.