Personally, I think we have quite a long way to go before we reach a point where that cannot ever be true and I think we should account for the possibility that humanity finds a way to keep expanding forever. Whether that be into the ocean or outer space or perhaps ever vertically on Earth. But those are problems for a thousand years from now and I don't think are as worthy of consideration in 2024.
What sort of other challenges do you see that need to be addressed first and foremost?