I probably have a unique preferred layout of Vim splits and tabs that I use for each codebase I work with. Being able to take this further, telling the editor which parts of code are significant and in which ways they go together, I'd have so much less mental overhead.
I love the idea that I could navigate our current codebase by endpoint, jumping to the account management portion of our API, automatically having the relevant back-end code and unit tests on-screen, along with benchmark info and test results. Since we adhere to general conventions at least within a project, there's no reason this can't be done.