>You can always use different databases for different use cases.
Unfortunately this is not always realistic, especially in large organizations, I know where I am there is a big push from top (i.e the IT budget people) to standardize everything they want to simplify licenses, support contracts etc.
I may not be doing cutting edge stuff (I work at an Industrial plant) but we do have mixed data use cases where it could be beneficial to use different dbs but realistically I don't see it happening.