The Congressional Budget Office writes plenty about this and throws out statements like the following
>Some economists are becoming concerned about diminished competition among firms—especially those firms involved in Internet-based commerce—and its harm to entrepreneurship, and about the impact of noncompete clauses
Information technology has drastically changed the business landscape in such a way that it no longer looks or acts like the pre-internet world. Furthermore global marketplaces like Amazon allow entrepreneurs to exist outside of the countries doing the counting.
I don't think it's true that it is harmless to society, and I don't think we fully understand what the ramifications will be.
What you're looking for is the principle of least harm. Time and time again we've proven that banning drugs is not the least harmful option. It turns out that humans really love vice which causes even more harmful black markets. We have lots of articles and information about drugs and their effects on society, you were attempting to link it to entrepreneurship of which from what can be seen is a very tenuous link at best.
Legalizing alcohol was for the best, because it eliminated the organized crime aspect. But it came with serious harms to society that we really haven't done a good job of mitigating. Alochol destroys so many lives and kills so many people each year.
I'm asking, how we can not make that mistake again. To be clear, whatever the harms of normalized cannabis use in society, it will be far less than alcohol.
