You say it like this is a point against autonomous trucking?
Technical problems are solvable. Political and social problems are basically intractable in practice.
If autonomous driving can turn 'delivering large amounts of cargo along fixed, guided pathways' from a political into a technical problem, then this would be a jackpot.
> [...] capitalism is designed to route around any such inefficiency as morals or safety standards until otherwise compelled by regulation.
No? Plenty of eg cars exceed minimum safety standards. Some brands, like Volvo, are even explicitly sold on safety. Most companies explicitly talk up their morals and ethics, too. Look at almost any old advertisement for examples. Ethical brands are quite popular, and whenever one is found to be only pretending, there's usually a big scandal. So many of them actually practice what they preach.
Similarly, most people are paid more than regulated minimums. According to your theory, that shouldn't happen.