QE simply swaps one form of government liability (treasuries) for another (reserves).
They pay less interest on reserves.
The effect on the economy of banks holding reserves rather than securities is otherwise negligible because both securities and reserves can be used to satisfy any liquidity requirements, so reserves and securities are functionally identical.
That’s why it’s so dumb that people get in a flap over the idea of the Treasury issuing reserves “out of thin air” but they are fine with the Tresury issuing new securities “out of thin air”.
They’re more or less the same operation.