the comments on that article from people who tried to use their boards are scathing

(the link to the not-yet-discontinued curie in that article is now a broken link, and the link https://communities.intel.com/community/tech/intel-curie from https://github.com/arduino/ArduinoCore-arc32, which hasn't been updated in 5 years, says 'The core node you are trying to access is permanently deleted.' https://www.intel.la/content/www/xl/es/products/sku/96282/in... says it's discontinued.)

this is very different from 30 years ago when pc104 boards were all over the place. pc104 is not completely forgotten but pc104 and vmebus are pretty well eclipsed by raspberry pi, esp32, arduino, gumstix, and plain stm32 and avr8 designs, increasingly even in non-hobbyist designs. can and i2c have displaced isa/eisa and sometimes even rs422

so if you are doing embedded work you probably will not be able to use amd64 or i386 and thus jonesforth or smithforth or stoneknifeforth. but the principles do apply