You can only fit 1-2 graphics cards in a “normal” ATX case (each card takes 2-3 “slots”). If you want 4 cards on one machine, you need a bigger/more expensive motherboard, case, PSU, etc. I haven’t personally seen anyone put 6 cards in a workstation.
In a water cooled config the cards only take 1 slot. I’ve got 2 3090s and am buying another two shortly. Preemtively upgraded the power to 220v, found a 2kw PSU, and installed a dedicated mini split. I’m also undervolting the cards to keep power and heat down, because even 2000w is not enough to run 4 and a server grade CPU without tripping. When you start accumulating GPUs you also run into all kinds of thermal and power problems for the room, too.
I was fortunate enough to scoop up a bunch of Gigabyte RTX 3090 Turbos. Cheap used eight slot SuperMicro (or whatever), a cabling kit, four 3090s, boot.
Sincere question: Is installing and running a mini split actually cheaper than racking them in a colo, or paying for time on one of the GPU cloud providers?
Regardless, I can understand the hobby value of running that kind of rig at home.
You have to pass the context between GPUs for large models that don't fit in VRAM. Often ends up slower. Also, tooling around AMD GPUs is still poor in comparison.
