Sometimes I think that really ambitious people have this blind spot about not seeing how accepting roles that are toxic can end up destroying your reputation. My favorite example is all the Trump White House staffers - regardless of what one thinks of Trump, he's made it abundantly clear that loyalty is a one way street, and I can't think of a single person that came out of the White House without a worse (or totally destroyed) reputation. But still people lined up, thinking "No way, I'll be the one to beat the odds!"