I mean discussions are typically both science and politics. Masks lower the amount of people that get sick is scientific fact; why do you think they wear them in the operating room? Whether or not that is "worth" wearing a mask is politics though. However, if you want to convince people of something (aka politics) you may want to appeal to them using logic and for that you'll want to use facts.
Having large variability doesn't make something not a fact. Plenty of males 20-24 do not get in car accidents but that doesn't mean that none of them will or that if you were to insure say 100k males 20-24 and 100k females 20-24 that the males wouldn't in aggregate have higher claims. But given a specific male and specific female its entirely possible that the female gets into an accident first.