I think the remark is because: MITM would allow them to spoof the DNS response entirely, so they can replace it with whatever key they want. Doesn't matter what level of security the key claims at that point, it's attacker-controlled and they can just read whatever you send next.
I think the DNS key is only for the handshake to provide the certificate for the actual key. Without a certificate from a CA for second part, all the spoofed DNS key would get is what website they were trying to visit.