One interpretation of "Zionism" could mean the idea that Israel should be an ethnically and religiously Jewish state that comprises the Biblical land of Israel, and that everyone else should be second-class citizens; and so simply saying that Israel should be a democracy that gives equal rights to all the people living within its borders, or that Israel should respect the Palestinian territories, would be "Anti-Zionist". Under this interpretation, "Anti-Zionism questions Israel's existence" really means "Anti-Zionism questions the existence of one particular vision for what Israel should be". That's not really a bad thing.
If, on the other hand, "Anti-Zionist" means the abolishing the Israeli government and re-partitioning the territory back into its pre-1948 states -- I mean, yeah, that's pretty bad; but I've never heard any of my left-leaning friends advocate anything like that, and such a desire would be really incompatible with everything else they're in favor of.
But these are just guesses, since you didn't provide much context.