There's a generic argument against DT, in any form, that was formulated back in the 1980s. All experience since then confirms the argument: it's that DT fusion reactors must have unacceptably low volumetric power density, much worse than fission reactors. This follows from limits on power/area at the reactor boundary and from minimum thickness of the blanket dictated by nuclear cross sections.
This will make the reactors much more expensive than fission reactors. And give that fission has proven to not be competitive, DT fusion has no chance.