If you're goal is ergonomics, the physical layout will get you 90% of the benefits. Ditching qwerty might get you that 10% but at a higher cost since almost all computing is built around qwerty.
Sure I was just thinking for most people. I just got a ZMK keyboard and I'm I've been practicing Coleman and qwerty. After less than an hour on Coleman, I was struggling on qwerty and had to wait for qwerty to switch back on my brain. Are you able to switch to qwerty with out issues if you need to?
I've been QWERTY-free since 2012. I do the layout in firmware so I don't need to change the mapping in the OS. And I use QMK and ZMK and I have a travel board that's bluetooth.
This concern might have been real back on OS/2 and MS-DOS. Not now.
