Yep, which is why I used the term "more lenient policies," not necessarily non-prohibition. Opium dens were getting more and more problematic in San Francisco[1] until they were criminalized in the late 19th century.
> I mean, people haven't really stopped doing Cocaine or Meth
I don't think the end goal of prohibition is zero use of said substance, but rather its control as to prevent large-scale societal disruption.
[1] https://www.foundsf.org/index.php?title=Chinatown%27s_Opium_...