Moreover, leaving things to the states is how slavery was allowed before the Civil War, and how black people continued to be oppressed even after they were technically freed. (Remember that poll taxes for example were not prohibited until 1964.) So no, I'm not particularly interested in leaving things to the states. To take a much more recent example, why should a woman's right to get an abortion depend on where she stands relative to some arbitrary state line?
I think it's silly and counterproductive to behave as if we have 50 separate countries, united only by "national" defense, or whatever one thinks the minimal requirements are. And we can see how the UK shot itself in the foot by stupidly leaving the EU. Local rule is not necessarily better rule.