As I said above, the current US regime at least has an economic interest in throttling the current Russian regime's economic and political prospects.
Remember the US these days is an energy exporter. Russia is a competitor in this market. The intensification of hostilities with Russia in the 2010s coincide with the US switching from a net importer of energy to one that is beginning to export more than it uses: https://www.eia.gov/todayinenergy/images/2019.01.29/main.png
But more importantly, Russia is a rival in control of the middle east and Africa as well.
And bonus for the G7 as well if the US and Canada (whose energy companies are on the whole dominated by US capital anyways) can get a significant market for liquified natural gas and other export energy products into Europe now that the trade relationship with Russia is disrupted.
It is a bit unclear how a Republican administration would behave if it replaced Biden's. It depends a lot on which sector has the ear/control of the president at that point. Trump's administration seemed to be tangled up in the Russian energy sector in a way that made it conflicted (e.g. Rex Tillerson as secretary of state, etc.)
It's all a bit cynical. But at the same time, Ukraine also needs to be defended on principle from an aggressive neighbour.