But, you will see that in most games RTA (Real Time Attack, speed running by humans, live) does choose different strategies than TAS (Tool Assisted Speedrun, still humans, but using tools to record and splice together a sequence of inputs for the game).

For a TAS you can justify taking fifty one-in-ten chances in a row, because every time it doesn't come off you just throw that away and re-record, so maybe you do a few hundred re-records for that section, not bad at all. In RTA that's never going to make any sense, it kills essentially 100% of runs.