That said, weight training completely transformed my relationship with my body. You can only lug a big hunk of iron into the air so many times before you start thinking about how much we really have in common with a gorilla. Yeah we grew opposable thumbs and a much more active prefrontal cortex, but 96% of our DNA is the same as theirs after all. By the pound we're mostly monkeys or something like them and it's a bit conceited to imagine otherwise.
If you're a knowledge worker who sits in a chair and thinks all day it's easy to believe you're nothing like a monkey, but strenuous exercise dispels that notion because it recruits all of your body's monkey systems and makes all of the parts of you work together. In retrospect it shouldn't be surprising at all that letting most of your anatomy wither away is unhealthy and puts you out of balance. It's like getting your car serviced but telling the shop that you only want them to look at the electronics.