The D-Wave ones surely can't (theoretically unproven if it's doing anything 'useful', even if 'quantum').The ones that others have, theoretically can in the 'awesome future', but as yet can't (too noisy).
Hype aside - the largest number factored using Shor on a physical device is 21 (unclear if they actually used the result of the factoring to design the circuits like they did with 15).