It would be at least possible to write a python plugin for the 'automatic1111' ui which allows you to simply input the QR text, and have it generate images based on a variety of possible configurations in batch so you can go through and pick the one which is most aesthetically pleasing.
edit: It would also be beneficial to have a script which automatically distorts the image in various ways and checks to see if it would be recognized by a QR code scanner, and give a score so you can see how likely it would be to be scannable in various conditions.